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  • Published on 20 Nov, 2025

    Updated on 20 Nov, 2025

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    3 min Read

In today’s busy world, where tight deadlines, digital overload, and silent struggles are common, mental health challenges are quietly reaching epidemic proportions. According to the World Health Organisation , over 280 million people worldwide are living with depression, and millions more are fighting anxiety, trauma, and burnout daily.

For many, the path to healing can seem never-ending. Traditional antidepressants often take weeks to show results. But imagine if there were a treatment that could offer relief in just hours? Learn about Ketamine Therapy, a once-controversial drug now gaining recognition as a potential breakthrough in mental health treatment. It helps in managing resistant depression and brings clarity after a long period of darkness, gaining recognition in the medical world.

But how does it work? Is ketamine therapy safe? Can ketamine transform mental health care? Let’s explore what ketamine therapy is and discover some amazing facts about one of the most talked-about treatments today.

What is Ketamine Therapy?

Ketamine originated in Belgium in the 1960s as an animal anaesthetic and was FDA-approved for human use in 1970. It was used for injured soldiers in the Vietnam War and is still used as an anaesthetic in surgery.

Ketamine therapy involves controlled, low doses of the drug, often combined with psychotherapy, to treat mental health issues and chronic pain, especially when traditional treatments fail. Unlike antidepressants that usually take weeks to work, ketamine offers quicker relief, often within hours or days. During therapy, ketamine is typically given via an IV infusion, nasal spray, or injection under the supervision of trained medical professionals.

Why is Ketamine Therapy Grabbing Attention?

Mental health care seeks faster, deeper, more effective solutions, especially for those who’ve tried everything else without improvement. Let’s explore why ketamine infusion therapy is getting attention:

  • Fast relief: One of ketamine therapy's most notable features is its quick action. Unlike conventional antidepressants that may take 4–6 weeks to become effective, ketamine can begin providing relief within hours. For individuals experiencing intense emotional distress or crisis, this swift response can be life-changing.
  • Hope for treatment-resistant cases: For many, standard medications and therapy aren’t sufficient. These individuals, known as having treatment-resistant depression, have tried various antidepressants with minimal or no progress. Ketamine offers new hope for these cases, reigniting optimism about recovery.
  • A broad range of uses: Scientists are exploring ketamine’s potential beyond depression. Early studies show it may reduce anxiety, PTSD, and suicidal thoughts. Some trials find it lowers suicidal ideation within hours, offering fast, potentially life-saving effects.

Who Can Receive Ketamine Therapy?

Ketamine therapy isn’t suitable for everyone, but it’s a thoughtful option for those who haven’t experienced enough relief from more traditional treatments. Typically, doctors suggest it for individuals with moderate to severe mental health challenges, especially when other methods haven't provided the desired results. Here’s who might find it most helpful:

  • People with treatment-resistant depression
  • Those experiencing intense suicidal thoughts
  • Individuals with particular anxiety or PTSD symptoms
  • Chronic pain or fibromyalgia patients (Under Guidance)

Conditions That Can Be Treated Through Ketamine Therapy

Ketamine therapy is a growing mental health treatment for various conditions. It influences the brain’s glutamate system to “reset” unhealthy patterns, offering hope for those unresponsive to traditional methods. Here are some main conditions treated with ketamine therapy:

  • Major Depressive Disorder (MDD)
  • Treatment-Resistant Depression (TRD)
  • Anxiety Disorders
  • Post-Traumatic Stress Disorder (PTSD)
  • Bipolar Depression
  • Obsessive-Compulsive Disorder (OCD)
  • Suicidal Ideation
  • Chronic Pain and Fibromyalgia
  • Eating disorders

What are the Side Effects of Ketamine Therapy?

Ketamine is generally regarded as safe, even for individuals with suicidal thoughts or plans. Its primary side effects include dissociation, intoxication, sedation, elevated blood pressure, dizziness, headache, blurred vision, anxiety, nausea, and vomiting. It's best to consider avoiding ketamine if you're in these particular groups.

  • People with a history of psychosis or schizophrenia should avoid ketamine, as its dissociative effects may worsen psychotic disorders.
  • People with a history of substance use disorder should be cautious, as ketamine can cause euphoria and addiction.
  • Teenagers, due to concerns about ketamine's long-term effects on the developing adolescent brain
  • Women who are pregnant or breastfeeding
  • Older adults exhibiting symptoms of dementia.

>> Read More: From Mind to Body: How Does Mental Health Affect Physical Wellness?

The Journey Toward Better Mental Wellness!

As the world begins to prioritise mental health, Ketamine Therapy stands out as a light of hope for those who have struggled with depression, anxiety, or trauma, with limited success. Ketamine can deliver rapid relief and revive positivity, making it one of the most promising breakthroughs in contemporary mental health care.

While treatment options continue to improve, the cost of care might still feel overwhelming for many. Having a comprehensive health insurance plan can significantly help you or your loved ones by providing access to advanced therapies like ketamine without financial stress. Choosing the right family health insurance isn’t just about paying bills; it’s about safeguarding your peace of mind, ensuring you get immediate help, and keeping your wellness journey smooth. Remember, when it comes to mental health, every moment and every decision truly counts.

Disclaimer: The above information is for reference purposes only. Kindly consult your general physician for verified medical advice. The health insurance benefits are subject to policy terms and conditions. Refer to your policy documents for more information.

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  • Your Queries Related

  • Q. Which conditions do Ketamine Therapy typically help treat?

    Ketamine treats many disorders like anxiety, depression, PTSD, OCD, fibromyalgia, migraines, chronic pain, substance misuse, neuropathic pain, and trigeminal neuralgia, showing potential for immediate results.

    Q. What are the benefits of ketamine treatment?

    Ketamine treatment offers significant benefits for mental health and pain relief, especially for conditions unresponsive to standard therapies.

    Q. What are the available ketamine treatment options?

    Ketamine treatments vary by administration: IV infusion, IM injection, nasal spray (esketamine), and oral lozenges or troches.

    Q. How does Ketamine therapy work?

    Ketamine acts as an N-methyl-D-aspartate (NMDA) receptor antagonist, increasing glutamate levels and supporting new neural connections to help repair stress-related damage.

    Q. Is Ketamine FDA-approved for depression?

    The FDA has not approved IV ketamine for depression and only approves it as an anaesthetic. However, esketamine (Spravato) is FDA-approved for certain depression-related conditions.

    Q. Who should not take ketamine therapy?

    People with uncontrolled high blood pressure, certain heart diseases, active mania or psychosis, or pregnant women (unless reviewed by a specialist) may not be suitable for ketamine therapy.

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